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Effective systemic dose in pigs of 1.1 mg/kg (~75 mg in humans) showed no adverse effects, representing approximately 300-fold below toxic dose

These findings underscore the need for a judicious and evidence-based approach in the formulation and administration of AOX supplements to ensure both their safety and therapeutic efficacy (36, 37)

The tripeptide structure allows receptor binding at minimal concentrations because the interaction is highly specific

This natural appetite suppression makes overeating less likely because the motivation simply isn't there